How repeated influenza vaccination effects may apply to COVID-19 vaccines
How repeated influenza vaccination effects may apply to COVID-19 vaccines

How repeated influenza vaccination effects may apply to COVID-19 vaccines

Many of the current issues of public health and the research aspects of the future of COVID-19 vaccines and vaccine strategies have been topics of research and debate in the influenza vaccine literature for decades. Here we describe how the experience from the study of repeated influenza vaccinations can apply to the evaluation of COVID-19 vaccines and the prospect of future seasonal or periodic booster vaccinations.

There are many differences between COVID-19 and influenza vaccines in their design and manufacture, immunological context and efficacy in preventing disease. Nevertheless, as both SARS-CoV-2 and influenza viruses are constantly evolving and may escape vaccine-induced immunity, and as protection from both vaccines decreases over time,

  • Ferdinands JM
  • Rao S
  • Dixon BE
  • et al.
Decreasing 2-dose and 3-dose efficacy of mRNA vaccines against COVID-19 associated emergency room and acute treatments and hospitalizations among adults during periods of delta and omicron variant dominance – VISION Network, 10 states, August 2021-January 2022 .