Immune-compromised people may need a fourth Covid-19 shot, CDC says – Community News

Immune-compromised people may need a fourth Covid-19 shot, CDC says

The CDC approved a third dose in August for certain immunocompromised people ages 18 and older. It said a third dose, rather than a booster — the CDC makes a distinction between the two — was needed because the immunocompromised may not have had a full immune response from the first two doses.
A study from Johns Hopkins University this summer showed that vaccinated immunocompromised people were 485 times more likely to end up in hospital or die from Covid-19 compared to most vaccinated people. In small studies, the CDC said, fully vaccinated immunocompromised people accounted for about 44% of breakthrough cases requiring hospitalization. People who are immunocompromised are also more likely to transmit the virus to people who have had close contact with them.

Research showed that a booster dose increased the antibody response to the vaccine in certain immunocompromised people.

That would yield a fourth injection, at least six months after completing the third mRNA vaccine dose. At this time, the CDC has no recommendation on the fourth shot. People should talk to their doctors to determine if it’s necessary, the CDC says.
Moderately to severely immunocompromised people include those on active cancer treatment for blood cancers or for tumors, certain organ transplant and stem cell recipients, those with advanced or untreated HIV, and those taking high-dose corticosteroids or other drugs that can suppress their immune system . The CDC estimates that about 9 million people living in the US, or about 2% of the population, fall into this category.

People who are immunocompromised and have received the single-dose Johnson & Johnson injection should receive a booster at least two months after their first vaccine. People who choose a Moderna vaccine as a booster, even if they received a different vaccine as their first dose, should receive half the dose that was approved as a booster for Moderna’s vaccine, the CDC said.

Even if they have been vaccinated, the CDC recommends that people with conditions that affect their immune system should still try to avoid crowds and poorly ventilated areas, and wear a mask in indoor public areas.

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