Providence study: COVID-19 infection granted

Providence study: COVID-19 infection granted

A study released in JAMA Network Open by investigators at Providence, one of the largest healthcare systems in the United States, and the University of Chicago, found that the level of protection provided by a previous symptomatic COVID-19 infection among unvaccinated individuals was on a par with the level of protection mRNA vaccines, with natural immunity, which provides a longer protection window than mRNA vaccines. The study was conducted before the advent of the highly transmissible omicron variant in the United States.

“We found that prior to the emergence of the omicron variant, natural immunity provided a similar degree of protection against COVID-19 infection as mRNA vaccination,” said Ari Robicsek, MD, Providence’s lead medical analyst and senior author of the study. “That said, vaccination is a significantly safer way to gain that immunity.”

Conducted by a team of expert clinicians and scientists within the Providence Research Network, the study examined data from over 100,000 patients tested for SARS-COV-2 at 1,300 nursing homes across Providence’s comprehensive health care system between October 1, 2020 and November 1, 2021. The researchers observed that previous COVID-19 infection was 85% protective against re-infection and 88% protective against hospitalization, with protection against re-infection lasting up to nine months after the first infection, as far as they were able to study .

The Providence study, one of the largest of its kind, shows the importance of connecting researchers with large-scale health data, and the impact an interconnected health system can have in understanding specific public health challenges. The study is unique, not only in scope but in its extensive follow-up period, and the inclusion of only unvaccinated individuals with symptomatic COVID-19.

“These data are key to helping us understand the strength and longevity of natural immunity and allow us to compare the efficacy of a previous infection with mRNA vaccines,” said Amy Compton-Phillips, MD, Providences chief clinical officer. “The results provide new insights into the length of protection following an initial infection among the unvaccinated population and may have important implications for vaccination guidelines and public health policies.”

About Providence
Providence is a national, not-for-profit Catholic health care system that includes a diverse family of organizations and is driven by a belief that health is a human right. With 52 hospitals, over 1,000 medical clinics, senior services, supportive housing and many other health and education services, the health system and its partners employ more than 120,000 caregivers serving communities in seven states – Alaska, California, Montana, New Mexico, Oregon, Texas and Washington. , with system offices in Renton, Washington and Irvine, California. Learn about our vision for health for a better world on Providence.org.


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