Some psychiatric conditions may increase the risk of COVID-19 breakthrough, the study shows
Some psychiatric conditions may increase the risk of COVID-19 breakthrough, the study shows

Some psychiatric conditions may increase the risk of COVID-19 breakthrough, the study shows

Vaccinated people with a history of certain psychiatric conditions may have a higher chance of incurring COVID-19 breakthroughs, according to a study published April 14 in JAMA Network Open.

Researchers from the University of California San Francisco and the San Francisco Veterans Affairs Health Care System led the study, which involved EHR data from 263,697 VA patients. About 51 percent of participants had received at least one psychiatric disorder diagnosis within the past five years. The disorders included depression, post-traumatic stress, anxiety, adjustment disorder, substance abuse disorder, bipolar disorder, psychosis, attention deficit / hyperactivity disorder, dissociation and eating disorders.

Three finds:

Of the 135,481 participants with at least one psychiatric disorder diagnosis, nearly 15 percent, or 39,109 individuals, developed a groundbreaking COVID-19 infection.

Overall, those with any psychiatric disorder had a 7 percent increased risk of developing a breakthrough infection compared to patients without psychiatric disorders.

3. Patients aged 65 years and older with substance abuse faced highest increased risk for breakthrough COVID-19 of 24 percent, followed by patients in the age group with psychotic disorders (23 percent); bipolar disorder (16 percent); adaptive disorder (14 percent); and anxiety (12 percent).

“Our results indicate that individuals with psychiatric disorders may be a high-risk group for COVID-19 and that this group should be prioritized for booster vaccinations and other critical preventive measures, including increased SARS-CoV-2 screening, public health campaigns, or COVID-19- discussions during clinical treatment, “the researchers wrote.

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